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Home»Science»St. Jude scientist named to STAT Wunderkind class of 2025 for research contributions
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St. Jude scientist named to STAT Wunderkind class of 2025 for research contributions

October 17, 2025No Comments
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Andrew Kleist, MD, PhD, has been named a 2025 Wunderkind by STAT, the influential health, medicine and life sciences publication. Kleist is a lead computational research scientist in the Center of Excellence for Data Driven Discovery, Department of Structural Biology, at St. Jude Children’s Research Hospital. He works in the laboratory of M. Madan Babu, PhD, FRS, senior vice president of Data Science, chief data scientist, Center of Excellence for Data-Driven Discovery director, and Department of Structural Biology member.

“It’s an honor to be recognized for this award and to be named among this group of up-and-coming leaders in the biomedical research field,” Kleist said. “I’m particularly indebted to my mentors, including Dr. Babu, who helped shape me as a scientist. Being recognized for this award is a testament to all of the mentorship and support I’ve received throughout my career.”

Each year, the STAT Wunderkind awards highlight the research of early-career scientists and clinicians making breakthrough discoveries in health, medicine and science. Other Wunderkinds from St. Jude include Daniel Blair, PhD, a member of the Department of Chemical Biology and Therapeutics, who was named to the list in 2022.

“Since joining our department, Andrew has made significant contributions to our understanding of influenza virus proteins and the chemokine receptor system, which governs cell movement and migration,” Babu said. “His research is providing new avenues to combat infectious diseases, develop new medicines and improve existing cell therapies.”

Kleist joined St. Jude in April 2025 and focuses his research on molecular-scale events and understanding the behavior of proteins by examining their 3-D structures. His current projects include researching mutations in influenza proteins and the impact on pathogenicity; how aberrant signaling through cell-surface receptors can lead to cancer progression; and how genetic-level variants affect protein structures and lead to human disease. His research has been featured in Cell, Science and Nature Genetics.

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